coronavirus type 2 among asymptomatic, RT-PCR-negative  members of the Croatian First League

Venkatesh B; Pavan kumar

doi:10.62649/

Authors

Venkatesh B Assistant professor, Department of Pharmaceutical Analysis, Swami Vivekananda College of Pharmacy, Srikakulam. Author
Pavan kumar Assistant professor, Department of Pharmacology, Swami Vivekananda College of pharmacy, Srikakulam. Author

DOI:

https://doi.org/10.62649/

Keywords:

COVID-19; seroprevalence; football; antibodies; ELISA; asymptomatic.

Abstract

The Croatian Football Federation used a novel concept of pre-season systematic evaluation of football players during the COVID-19 pandemic, with the goal of identifying asymptomatic cases of SARS-CoV-2 infection and stopping their spread among the team's players. Using a commercial ELISA antibody assay on paired serum samples collected 2 months apart, this study aimed to determine the prevalence and dynamics of SARS-CoV-2 IgA and IgG antibodies in a cohort of asymptomatic and SARS-CoV-2 PCR-negative professional football players in the Croatian First Football League. Methods From May-July of 2020, a group of 305 asymptomatic football players and club staff members underwent serology testing. Euroimmun ELISA was used in May and July to screen matched blood samples for IgA and IgG (S1 and NCP) antibodies, and real-time polymerase chain reaction (RT-PCR) was used on three separate occasions to identify SARS-CoV-2 from nasopharyngeal swabs.